K. de Strooper: search on Z-Library

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1

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

Karran, Eric, Mercken, Marc, Strooper, Bart De

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 931 KB

english, 2011

2

Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency

Vos, M., Esposito, G., Edirisinghe, J. N., Vilain, S., Haddad, D. M., Slabbaert, J. R., Van Meensel, S., Schaap, O., De Strooper, B., Meganathan, R., Morais, V. A., Verstreken, P.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.59 MB

english, 2012

3

Alzheimer's disease

Scheltens, Philip, Blennow, Kaj, Breteler, Monique M B, de Strooper, Bart, Frisoni, Giovanni B, Salloway, Stephen, Van der Flier, Wiesje Maria

Journal:

Year:

2016

Language:

english

File:

PDF, 321 KB

english, 2016

4

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

Benilova, Iryna, Karran, Eric, De Strooper, Bart

Journal:

Nature Neuroscience

Year:

2012

Language:

english

File:

PDF, 544 KB

english, 2012

5

Drosophila transgenic RNAi screen of genes implicated in human neurological disease

Dominik M. Haddad⁎, Melissa Vos, Vanessa A. Morais, Maarten Leyssen, Joke Allemeersch, Bart De Strooper, Patrik Verstreken

Journal:

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

6

The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

Arranz, Amaia M, De Strooper, Bart

Journal:

The Lancet Neurology

Year:

2019

Language:

english

File:

PDF, 473 KB

english, 2019

7

Subsurface water flow on a slope in the loamy region of Belgium

P. Michiels, R. Hartmann, E. De Strooper

Journal:

Earth Surface Processes and Landforms

Year:

1989

Language:

english

File:

PDF, 576 KB

english, 1989

8

The World of Dementia Beyond 2020

Henry Brodaty, Monique M. B. Breteler, Steven T. DeKosky, Pascale Dorenlot, Laura Fratiglioni, Christoph Hock, Paul-Ariel Kenigsberg, Philip Scheltens, Bart De Strooper

Journal:

Journal of the American Geriatrics Society

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

9

10.1038/19083

De Strooper, Bart, Kopan, Raphael, Annaert, Wim, Cupers, Philippe, Saftig, Paul, Craessaerts, Katleen, Mumm, Jeffrey S., Schroeter, Eric H., Schrijvers, Vincent, Wolfe, Michael S., Ray, William J., Go

Journal:

Year:

1999

Language:

english

File:

PDF, 543 KB

english, 1999

10

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, Bruno Bergmans, Aikaterini S. Papadopoulou, André Delacourte, Bart De Strooper

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 756 KB

english, 2009

11

Non-coding RNAs with essential roles in neurodegenerative disorders

Evgenia Salta, Bart De Strooper

Journal:

The Lancet Neurology

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

12

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

Hebert, S. S., Horre, K., Nicolai, L., Papadopoulou, A. S., Mandemakers, W., Silahtaroglu, A. N., Kauppinen, S., Delacourte, A., De Strooper, B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 946 KB

english, 2008

13

Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations

Huiping Tu, Omar Nelson, Arseny Bezprozvanny, Zhengnan Wang, Sheu-Fen Lee, Yi-Heng Hao, Lutgarde Serneels, Bart De Strooper, Gang Yu, Ilya Bezprozvanny

Journal:

Year:

2006

Language:

english

File:

PDF, 957 KB

english, 2006

14

Gene Dosage Effect on γ-Secretase Component Aph-1b in a Rat Model for Neurodevelopmental Disorders

Marcel W. Coolen, Karen M.J. Van Loo, Nick N.H.M. Van Bakel, David J. Pulford, Lutgarde Serneels, Bart De Strooper, Bart A. Ellenbroek, Alexander R. Cools, Gerard J.M. Martens

Journal:

Year:

2005

Language:

english

File:

PDF, 325 KB

english, 2005

15

Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex

Bart De Strooper

Journal:

Year:

2003

Language:

english

File:

PDF, 65 KB

english, 2003

16

Deficiency of Aph1B/C- -secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment

Dejaegere, T., Serneels, L., Schafer, M. K., Van Biervliet, J., Horre, K., Depboylu, C., Alvarez-Fischer, D., Herreman, A., Willem, M., Haass, C., Hoglinger, G. U., D'Hooge, R., De Strooper, B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

17

Tudca, a bile acid, attenuates amyloid beta deposition and rescues memory deficits in app/ps1 mice

Nunes, Ana, Fonseca, Maria, Viana, Ricardo, Lo, Adrian, De Strooper, Bart, D'Hooge, Rudi, Rodrigues, Cecília

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 73 KB

english, 2011

18

Cholesterol Depletion Inhibits the Generation of β -amyloid in Hippocampal Neurons

Mikael Simons, Patrick Keller, Bart De Strooper, Konrad Beyreuther, Carlos G. Dotti and Kai Simons

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.24 MB

english, 1998

19

Methylation Analysis of the FAM19A4 Gene in Cervical Scrapes Is Highly Efficient in Detecting Cervical Carcinomas and Advanced CIN2/3 Lesions

De Strooper, L. M. A., Meijer, C. J. L. M., Berkhof, J., Hesselink, A. T., Snijders, P. J. F., Steenbergen, R. D. M., Heideman, D. A. M.

Journal:

Cancer Prevention Research

Year:

2014

Language:

english

File:

PDF, 957 KB

english, 2014

20

Lessons from a Failed γ-Secretase Alzheimer Trial

De Strooper, Bart

Journal:

Year:

2014

Language:

english

File:

PDF, 666 KB

english, 2014

21

Learning by Failing: Ideas and Concepts to Tackle γ-Secretases in Alzheimer's Disease and Beyond

De Strooper, Bart, Chávez Gutiérrez, Lucía

Journal:

Annual Review of Pharmacology

Year:

2015

Language:

english

File:

PDF, 793 KB

english, 2015

22

Active -Secretase Complexes Contain Only One of Each Component

Sato, T., Diehl, T. S., Narayanan, S., Funamoto, S., Ihara, Y., De Strooper, B., Steiner, H., Haass, C., Wolfe, M. S.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 581 KB

english, 2007

23

Differential contribution of the three Aph1 genes to -secretase activity in vivo

Serneels, L., Dejaegere, T., Craessaerts, K., Horre, K., Jorissen, E., Tousseyn, T., Hebert, S., Coolen, M., Martens, G., Zwijsen, A., Annaert, W., Hartmann, D., De Strooper, B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 685 KB

english, 2005

24

A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases

Mandemakers, W., Morais, V. A., De Strooper, B.

Journal:

Journal of Cell Science

Year:

2007

Language:

english

File:

PDF, 635 KB

english, 2007

25

Notch Is a Critical Component of the Mouse Somitogenesis Oscillator and Is Essential for the Formation of the Somites

Ferjentsik, Zoltan, Hayashi, Shinichi, Dale, J. Kim, Bessho, Yasumasa, Herreman, An, De Strooper, Bart, del Monte, Gonzalo, de la Pompa, Jose Luis, Maroto, Miguel, Henry, Clarissa A.

Journal:

Year:

2009

Language:

english

File:

PDF, 4.80 MB

english, 2009

26

Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women

De Strooper, Lise M.A., Verhoef, Viola M.J., Berkhof, Johannes, Hesselink, Albertus T., de Bruin, Helena M.E., van Kemenade, Folkert J., Bosgraaf, Remko P., Bekkers, Ruud L.M., Massuger, Leon F.A.G.,

Journal:

Gynecologic Oncology

Year:

2016

Language:

english

File:

PDF, 748 KB

english, 2016

27

Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study)

Luttmer, Roosmarijn, De Strooper, Lise M.A., Berkhof, Johannes, Snijders, Peter J.F., Dijkstra, Maaike G., Uijterwaal, Margot H., Steenbergen, Renske D.M., van Kemenade, Folkert J., Rozendaal, Lawrenc

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 456 KB

english, 2016

28

COMPARISONS OF THE UNSATURATED HYDRAULIC CONDUCTIVITY OF A COARSE-TEXTURED SOIL AS DETERMINED IN THE FIELD, IN THE LABORATORY, AND WITH MATHEMATICAL MODELS

MICHIELS, P., HARTMANN, R., STROOPER, E. DE

Journal:

Year:

1989

File:

PDF, 376 KB

1989

29

Amyloid Precursor Protein Accumulation in Lewy Body Dementia and Alzheimers Disease

Van Gool, D., De Strooper, B., Van Leuven, F., Dom, R.

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

1995

File:

PDF, 2.42 MB

1995

30

Inactivation of γ‐secretases leads to accumulation of substrates and non‐Alzheimer neurodegeneration

Acx, Hermien, Serneels, Lutgarde, Radaelli, Enrico, Muyldermans, Serge, Vincke, Cécile, Pepermans, Elise, Müller, Ulrike, Chávez‐Gutiérrez, Lucía, De Strooper, Bart

Journal:

EMBO Molecular Medicine

Year:

2017

Language:

english

File:

PDF, 5.90 MB

english, 2017

31

Diabetes and Alzheimer’s Disease: A Link not as Simple as it Seems

Salas, Isabel H., De Strooper, Bart

Journal:

Neurochemical Research

Year:

2018

Language:

english

File:

PDF, 836 KB

english, 2018

32

Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Rice, Heather C., Marcassa, Gabriele, Chrysidou, Iordana, Horré, Katrien, Young-Pearse, Tracy L., Müller, Ulrike C., Saito, Takashi, Saido, Takaomi C., Vassar, Robert, de Wit, Joris, De Strooper, Bart

Journal:

Molecular Neurodegeneration

Year:

2020

Language:

english

File:

PDF, 2.38 MB

english, 2020

33

Cancer and neurodegeneration meet

Bart De Strooper

Journal:

EMBO Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 78 KB

english, 2010

34

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

Iryna Benilova, Bart De Strooper

Journal:

EMBO Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

35

Notch pathway is dispensable for adipocyte specification

Amy M. Nichols, Yonghua Pan, An Herreman, Brandon K. Hadland, Bart De Strooper, Raphael Kopan, Stacey S. Huppert

Journal:

Year:

2004

Language:

english

File:

PDF, 299 KB

english, 2004

36

Alzheimer dementia caused by a novel mutation located in the APP C-terminal intracytosolic fragment

J. Theuns, E. Marjaux, M. Vandenbulcke, K. Van Laere, S. Kumar-Singh, G. Bormans, N. Brouwers, M. Van den Broeck, K. Vennekens, E. Corsmit, M. Cruts, B. De Strooper, C. Van Broeckhoven, R. Vandenbergh

Journal:

Year:

2006

Language:

english

File:

PDF, 313 KB

english, 2006

37

α2-macroglobulin and subacute-phase responses in Alzheimer's disease

Bart De Strooper, Fred Van Leuven

Journal:

Immunology Today

Year:

1993

Language:

english

File:

PDF, 134 KB

english, 1993

38

Magnetic properties of the spinel series Co2−yZnyTiO4 (0 ⩽ y ⩽ 1)

K. De Strooper, G. Robbrecht

Journal:

Year:

1977

Language:

english

File:

PDF, 154 KB

english, 1977

39

The amyloid precursor protein (APP)-cytoplasmic fragment generated by γ-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

Philippe Cupers, Isabelle Orlans, Katleen Craessaerts, Wim Annaert, Bart De Strooper

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 675 KB

english, 2001

40

Gene profiling of hippocampal neuronal culture

Michal Dabrowski, Stein Aerts, Paul Van Hummelen, Katleen Craessaerts, Bart De Moor, Wim Annaert, Yves Moreau, Bart De Strooper

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 314 KB

english, 2003

41

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion proteinin vivo

Hermann C Altmeppen, Johannes Prox, Berta Puig, Mark A Kluth, Christian Bernreuther, Dana Thurm, Ellen Jorissen, Bettina Petrowitz, Udo Bartsch, Bart De Strooper, Paul Saftig, Markus Glatzel

Journal:

Molecular Neurodegeneration

Year:

2011

Language:

english

File:

PDF, 4.17 MB

english, 2011

42

Magnetic properties of the spinel series Co2GexTi1−x O4 (0 ≦ x ≦ 1)

K. De Strooper, A. Govaert, C. Dauwe, G. Robbrecht

Journal:

physica status solidi (a)

Year:

1976

Language:

english

File:

PDF, 341 KB

english, 1976

43

Magnetic properties of some Co2+ containing spinels

Journal:

physica status solidi (a)

Year:

1977

Language:

english

File:

PDF, 329 KB

english, 1977

44

Magnetic properties of Fe2P

M. Wautelet, A. Gérard, F. Grandjean, K. de Strooper, G. Robbrecht

Journal:

physica status solidi (a)

Year:

1977

Language:

english

File:

PDF, 389 KB

english, 1977

45

On the cation distribution and magnetic properties of cobalt–zinc titanates

K. De Strooper, A. van Alboom, C. Henriet-Iserentant, R. Vanleerberghe, R. Vandenberghe

Journal:

physica status solidi (a)

Year:

1977

Language:

english

File:

PDF, 331 KB

english, 1977

46

Neurons Generated from APP/APLP1/APLP2 Triple Knockout Embryonic Stem Cells Behave Normally in Vitro and in Vivo: Lack of Evidence for a Cell Autonomous Role of the Amyloid Precursor Protein in Neuronal Differentiation

Bruno A. Bergmans, S. Ali M. Shariati, Ron L.P. Habets, Patrik Verstreken, Luc Schoonjans, Ulrike Müller, Carlos G. Dotti, Bart De Strooper

Journal:

Year:

2010

Language:

english

File:

PDF, 849 KB

english, 2010

47

The function of presenilin-1 in amyloid β-peptide generation and brain development

P. Saftig, D. Hartmann, B. De Strooper

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

48

Conserved residues within the putative active site of γ-secretase differentially influence enzyme activity and inhibitor binding

Jonathan D. J. Wrigley, Emma J. Nunn, Omar Nyabi, Earl E. Clarke, Peter Hunt, Alan Nadin, Bart De Strooper, Mark S. Shearman, Dirk Beher

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

49

Presenilin clinical mutations can affect γ-secretase activity by different mechanisms

Mostafa Bentahir, Omar Nyabi, Jan Verhamme, Alexandra Tolia, Katrien Horré, Jens Wiltfang, Hermann Esselmann, Bart De Strooper

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 771 KB

english, 2006

50

The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing

Sabine Rabe, Julia Reichwald, Domenico Ammaturo, Bart de Strooper, Paul Saftig, Ulf Neumann, Matthias Staufenbiel

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

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